منابع مشابه
Soemmerring and the Substantia Nigra
REFERENCES 1. BALY, F. A., History ofSouthport, Southport, Angus Downie, 1955, p. 37. 2. BmuxmHourr, J., An Essay on the Bite of a Mad Dog, London, R. Baldwin, 1783. 3. British Museum, Add. MS. 36876. 4. FoHRGLL, J., 'The Case of a Hydrophobia', in: Medical Observations and Enquiries, 2nd ed., 1779, vol. 5, p. 195. 5. HBYSHAM, J., Dissertatio Medica de Rabie Canina, Edinburgh, 1777. Information...
متن کاملCulture of Substantia Nigra Neurons
Primary cultures of nigral tissue are widely used as a model system to assay effects of trophic and toxic agents on dopaminergic neurons. Cultured dopaminergic neurons have been successfully transplanted in animals and led to behavioral improvement in animal models of Parkinson’s disease. The success of these preclinical studies has encouraged investigators to begin clinical trials using transp...
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The aim of our study was to investigate the relation between substantia nigra (SN) echomorphology and indices of motor cortex excitability. Nigral hyperechogenicity in healthy individuals is thought to represent an SN abnormality or predisposition to Parkinson's disease (PD) and its prevalence is greater in the very old. Our study involved 20 old healthy subjects (aged 72-84 years) known to hav...
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The substantia nigra (SN) is known to be involved in the memorization of several conditioned responses. To investigate the role of the SN in fear conditioning consolidation this neural site was subjected to fully reversible tetrodotoxin (TTX) inactivation during consolidation in adult male Wistar rats which had undergone fear training to acoustic CS and context. TTX was stereotaxically administ...
متن کاملIdentification of proteins in human substantia nigra.
Characterization of the human brain proteome is a critical area of research. While examination of the human cortex has provided some insight, very little is known about the proteome of the human midbrain, which demonstrates substantial loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc) in Parkinson's disease (PD). Therefore, characterization of this region is essential to...
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ژورنال
عنوان ژورنال: The Journal OF Nervous and Mental Disease
سال: 1909
ISSN: 0022-3018
DOI: 10.1097/00005053-190909000-00023