THE SPOT URINE PROTEIN CREATININE RATIO- HAS IT GOT REAL SIGNIFICANCE IN STAGING OF CHRONIC KIDNEY DISEASES?

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Correlation between the protein/creatinine ratio in spot urine and 24-hour urine protein.

INTRODUCTION Measurement of the protein content in a 24-hour urine sample is the definitive method of establishing the presence of abnormal proteinuria. However, the urine collection is cumbersome. The spot urine protein to creatinine ratio seems to be a reliable diagnostic tool for urine protein measurement. OBJECTIVE Our aim was to evaluate the spot urine protein/creatinine ratio against 24...

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Correlation versus agreement; protein/creatinine ratio in spot urine and 24-hour urine protein.

Montero et al. do report the 95% limits on the Bland-Altman plot, perhaps the authors could have reported the 95% limits of agreement for a specific number of thresholds of proteinuria for example <300mg, <3.5 grams or >3.5 grams individually which would be useful for clini-cians trying to interpret spot urine pro-tein/creatinine ratio. I worry that readers of this excellent study may be left f...

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Comparison of spot urine protein creatinine ratio with 24 hour urine protein for estimation of proteinuria.

The objective of our study was to evaluate and standardise the method of spot (random) urine protein creatinine ratio (UP/C) for estimation of proteinuria. The study contained 241 study participants in a tertiary care hospital inclusive of 208 cases and 33 normal volunteers. The 24 hour urine protein estimation was done on 24 hour urine samples and UP/C ratio was calculated on random urine samp...

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Spot urine osmolality/creatinine ratio in healthy humans.

BACKGROUND Spot urine albumin/creatinine ratio is a reliable estimate of 24-hour urine albumin excretion. In a pilot study, we observed that the spot urine osmolality/creatinine ratio (U(osm)/U(cr)) in healthy adults is reproducible. Therefore, we postulated that U(osm)/U(cr) of a spot urine sample may give an overall estimate of urinary excretion of solutes, renal concentrating ability and bod...

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Assessing proteinuria in chronic kidney disease: protein-creatinine ratio versus albumin-creatinine ratio.

BACKGROUND Quantification of proteinuria is important in the assessment of chronic kidney disease (CKD). The aim of this study was to investigate the optimal test to identify significant proteinuria. METHODS We retrospectively assessed the relationship between total protein:creatinine ratio (TPCR), albumin:creatinine ratio (ACR) and 24-h urine total protein in 6842 patients with CKD focusing ...

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ژورنال

عنوان ژورنال: Journal of Evidence Based Medicine and Healthcare

سال: 2018

ISSN: 2349-2562,2349-2570

DOI: 10.18410/jebmh/2018/180