The Spermine Phosphate-Bound Cyclooctaoxygen Sodium Epigenetic Shell of Euchromatin DNA Is Destroyed by the Epigenetic Poison Glyphosate
نویسندگان
چکیده
Oxygen exists in two gaseous (dioxygen and ozone) six solid allotropic modifications. An additional modification of oxygen, the cyclooctaoxygen, was predicted to exist 1990. The first synthesis characterization cyclooctaoxygen as its sodium crown complex, isolated form three cytosine nucleoside hydrochloride complexes, reported 2016. sperminium hydrogen phosphate/cyclooctaoxygen complex calculated cover actively transcribed regions (2.6%) bovine lymphocyte interphase genome. Cyclooctaoxygen seems be naturally absent hypoxia-induced highly condensed chromatin, taken a model for eukaryotic metaphase/anaphase/early telophase mitotic chromatin. Hence, it is proposed that sodium-bridged phosphate selenite coverage serves an epigenetic shell gene ‘open’ euchromatin DNA. serve marker component at ATG start codons human DNA mRNA genes, both translation initiation triplet 5′-untranslated region upstream ATGs. total herbicide glyphosate (ROUNDUP®) metabolite (aminomethyl)phosphonic acid (AMPA) are proved represent ‘epigenetic poisons’, since they selectively destroy complex. This definition reason, destruction certainly sufficient bring protection shield into collateral collapse. environmental can associated vitro with catalytic detoriation genetic information. susceptible decay induced by poisons threatening genomic heritage.
منابع مشابه
The Spermine Phosphate-Bound Cyclooctaoxygen Sodium Epigenetic Shell of Euchromatin DNA Is Destroyed by the Epigenetic Poison Glyphosate
Oxygen exists in two gaseous and six solid allotropic modifications. An additional allotropic modification of oxygen, the cyclooctaoxygen, was predicted to exist in 1990. The first synthesis and characterization of cyclooctaoxygen as its sodium crown complex, isolated in the form of three cytosine nucleoside hydrochloride complexes, was reported in 2016. Cyclooctaoxygen sodium was synthesized f...
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ژورنال
عنوان ژورنال: Archives of clinical and biomedical research
سال: 2023
ISSN: ['2572-5017']
DOI: https://doi.org/10.26502/acbr.50170331