The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease
نویسندگان
چکیده
منابع مشابه
PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.
The adrenal cortex undergoes remodeling during fetal and postnatal life. How zona reticularis emerges in the postnatal gland to support adrenarche, a process whereby higher primates increase prepubertal androgen secretion, is unknown. Using cell-fate mapping and gene deletion studies in mice, we show that activation of PKA has no effect on the fetal cortex, while it accelerates regeneration of ...
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2021
ISSN: 1422-0067
DOI: 10.3390/ijms22094889