The Role of Topical Vitamin D in Vitiligo: A Narrative Literature Review

Vitamin D plays a role in the process of melanogenesis, namely increasing L-Dopa cells, inducing differentiation immature melanocytes, and melanocyte activity. The use vitamin dermatology is treatment vitiligo, psoriasis vulgaris, atopic dermatitis, verruca alopecia. Vitiligo an autoimmune disease skin form depigmentation due to destruction melanocytes by T cells. clinical manifestations vitiligo are white macular lesions no scale, asymptomatic, symmetrical. can affect patient's quality life, so accurate therapy needed. Standard needs further research find with minimal side effects. Topical Several types topical therapeutic effects field calcipotriol, calcitriol, tacalcitol, maxacalcitol, hexafluoro-1,25 dihydroxyvitamin D3 various dosages preparations. melanogenesis immunomodulators as monotherapy or combination corticosteroids has been shown be effective vitiligo. This literature review was on