The Role of Gut Microbiome in Psoriatic Arthritis—A Literature Review

Psoriatic arthritis is a heterogeneous chronic autoimmune disorder characterized principally by skin lesions, arthritis, dactylitis and enthesitis. The exact etiology of the disease yet to be discovered, with genetic predisposition alongside environmental factors being well-known theory. In recent years, new discoveries have emphasized role gut microbiome in perpetuating inflammation spondylarthritis. mechanism through which dysbiosis underlies pathophysiology psoriatic not defined. One current areas focus rheumatic research studies emerging annually link between arthritis. this review, we synthesized knowledge on intestinal We screened two databases for articles, PubMed Medline, using following keywords: “microbiome”, “microbiota” “psoriatic arthritis”. described expertise diversity composition comparing results other inflammatory diseases. future, preventing process that leads development could open door therapeutic modalities. Moreover, fecal microbiota transplantation probiotics’ benefits modulating are intensively researched at moment.