The Resurgence of Tuberculosis

Resurgence of paediatric tuberculosis in London.

There is estimated to be over a million new cases of paediatric tuberculosis (TB) globally every year. Children usually acquire TB infection from smear positive adult family contacts, a high proportion going on to develop disease. Childhood disease reflects recent infection, and therefore paediatric TB represents continuing transmission in the population. In England and Wales, TB notifications ...

Resurgence of tuberculosis and the impact of HIV infection.

Tuberculosis is increasing in many countries. In some areas the major influences on tuberculosis trends are the traditional ones: poverty, failures in the treatment system, and immigration. In others, and increasingly, the HIV epidemic is having a huge impact. HIV infection increases the risk of tuberculosis approximately 7-fold, though this may vary with the stage of the HIV epidemic, the prev...

The resurgence of tuberculosis and the impact of the study of pulmonary immunopathogenesis*

The resurgence of tuberculosis as one of the most important infectious diseases to affect mankind came after the illusion that the disease was under control and would be eradicated before the end of the 20th Century. Over the last 10 years, in association with American and European research centers, our group at the Universidade Federal do Rio de Janeiro has been dedicated to investigating the ...

The resurgence of tuberculosis in the Republic of Ireland: perceptions and reality.

Tuberculosis remained a very significant cause of death in Ireland until the mid-20th century and still occupies a prominent position in the folk memory. As I show with reference to recent Irish media coverage, the global resurgence of tuberculosis is therefore viewed with concern in Ireland. Using data collated by the Health Protection Surveillance Centre between 1998 and 2005 however, I show ...

Biologics and tuberculosis risk: the rise and fall of an old disease and its new resurgence.