The Research of Major Histocompatibility Complex (MHC) Gene in Small Mammals
نویسندگان
چکیده
منابع مشابه
The Research of Major Histocompatibility Complex (MHC) Gene in Small Mammals
MHC gene is a group of highly polymorphic genes. The structure, function and genetic characteristics of MHC gene have been revealed, in recent years, by more and more researchers. This study reviews the MHC in small mammals’ research, mainly on the domestic and foreign small mammals MHC gene polymorphism, and pays attention to the population genetic evolution and gene structure. The future rese...
متن کاملSimulation of Major Histocompatibility Complex (MHC) Structure and Peptide Loading into an MHC Binding Pocket with Teachers’Hands
Molecular understanding of three-dimensional (3D) peptide: MHC models require both basic knowledge of computational modeling and skilled visual perception, which are not possessed by all students. The present model aims to simulate MHC molecular structure with the hands and make a profound impression on the students.
متن کامل'Ovar-Mhc' - ovine major histocompatibility complex: structure and gene polymorphisms.
The major histocompatibility complex (MHC) in sheep, Ovar-Mhc, is poorly characterised, when compared to other domestic animals. However, its basic structure is similar to that of other mammals, comprising class I, II and III regions. Currently, there is evidence for the existence of four class I loci. The class II region is better characterised, with evidence of one DRA, four DRB (one coding a...
متن کاملThe Major Histocompatibility Complex (MHC) in Schizophrenia: A Review
Epidemiological studies and mouse models suggest that maternal immune activation, induced clinically through prenatal exposure to one of several infectious diseases, is a risk factor in the development of schizophrenia. This is supported by the strong genetic association established by genome wide association studies (GWAS) between the human leukocyte antigen (HLA) locus and schizophrenia. HLA ...
متن کاملMajor Histocompatibility Complex (MHC) Markers in Conservation Biology
Human impacts through habitat destruction, introduction of invasive species and climate change are increasing the number of species threatened with extinction. Decreases in population size simultaneously lead to reductions in genetic diversity, ultimately reducing the ability of populations to adapt to a changing environment. In this way, loss of genetic polymorphism is linked with extinction r...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Bioprocess
سال: 2016
ISSN: 2164-5566,2164-5582
DOI: 10.12677/bp.2016.63007