THE RENAL CLEARANCE OF ENDOGENOUS “CREATININE” IN MAN
نویسندگان
چکیده
منابع مشابه
The Renal Clearance of Endogenous "creatinine" in Man.
The existing methods for the analysis of inulin, as well as the requirements for the continuous intravenous infusion of this material, place the inulin clearance method for measuring the glomerular filtration rate beyond the reach of practicality for many laboratories and in general limit clearance observations to relatively short intervals of time. There is a requirement for a simpler clearanc...
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In normal subjects the glomerular filtration rate is relatively constant under standard conditions, and there is little or no change when the urine flow 'aries. It follows from this that the excretion rate of substances, which are filtered at the glomerulus and neither reabsorbed from nor secreted into the tubules, is constant. It is these substances which can be used to measure the filtration ...
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One of the troubles of using the endogenous creatinine clearance to measure the filtration rate is that plasma and serum contain chromogens, other than creatinine, which give a colour with the Jaffe reaction. The creatinine can, however, be isolated by adsorption on Fuller's earth (Gaebler and Keltch, 1928) and subsequently eluted with the alkaline picrate used for colour production (Borsook, 1...
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In a previous paper the evidence on the excretion of carbohydrates by the toadfish, goosefish, dogfish, dog and man was reviewed and it was concluded that, until evidence to the contrary is adduced, all the available facts are best interpreted on the supposition that pure carbohydrates in general are not secreted by the renal tubules of any of the above-mentioned forms (Shannon and Smith, 1935)...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1948
ISSN: 0021-9738
DOI: 10.1172/jci102012