The Renaissance of Primary Aldosteronism: What Has it Taught Us?

ALLHAT: what has it taught us so far?

What Has 30 Years of HIV Vaccine Research Taught Us?

When HIV was discovered and established as the cause of AIDS in 1983-1984, many people believed that a vaccine would be rapidly developed. However, 30 years have passed and we are still struggling to develop an elusive vaccine. In trying to achieve that goal, different scientific paradigms have been explored. Although major progress has been made in understanding the scientific basis for HIV va...

Anti-TNF therapy, from rationale to standard of care: what lessons has it taught us?

In the mid-1980s, new molecular tools enabled the biology of cytokine expression and regulation to be studied. Our group uncovered a TNF-dependent cascade in active rheumatoid synovium, suggesting that TNF might be a therapeutic target; this concept was supported in an animal model of the disease. The proof of concept was a series of clinical trials, which have led to marked changes in the ther...

What has nanotechnology taught us about contemporary technoscience ?

Nanotechnology has emerged as one of the dominating themes of international science policy in the last decade. I argue that, rather than considering this as the emergence of a new scientific field, nanotechnology is best thought of as a socio-political project that has arisen as a result of influences both from within science, and from the wider political, economic and cultural climate.

What qualitative research has taught us about occupational stress.

While many reviews of job stress and the stressor–strain relationship have been conducted, such reviews typically focus exclusively on quantitative data. In the current paper, we review qualitative studies on occupational stress that met two criteria: (1) the studies employed qualitative methods; (2) the stressors, strains and/or coping strategies were grouped into identifiable, higher-order ca...