The Relationship between IL-1β [-31 T/C] Gene Polymorphism and Symptomatic Lumbar Disc Herniation
نویسندگان
چکیده
In this study, the relationship between IL-1β [-31 C / T] gene polymorphisms in herniated lumbar disc is offered to be investigated. was amplified by PCR [Polymerase Chain Reaction] method. Polymorphic site cut with restriction enzyme Alu I and genotyping were performed. Fifteen subjects (15%) homozygous for C/C allele at -31 position of gene. Of remaining 85 subjects, 64 (64%) heterozygous C/T 21 (21%) T/T. LDH group, fifteen (30%) T/T 35 (70%). There significant differences control group. genotype higher than however group higher. not determined -31T shown associated Lumbar disc.
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ژورنال
عنوان ژورنال: Mu?la S?tk? Koçman üniversitesi t?p dergisi
سال: 2023
ISSN: ['2148-8118', '2618-6020']
DOI: https://doi.org/10.47572/muskutd.1186191