The protective role of parsley extract against vincristine mutagenicity in Drosophila melanogaster
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چکیده
منابع مشابه
Mutagenicity of nickel sulphate in Drosophila melanogaster.
Nickel sulphate was injected into Drosophila melanogaster males at different concentrations in order to test the chemical for the induction of SLRL and SCL in germ cells. Nickel sulphate induced SLRL at concentrations tested, with the peak of activity at premeiotic and postmeiotic stages. It failed to produce SCL except at the highest concentration tested, where induction of XO males was signif...
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Introduction: Vincristine (VCR) is potential anti-cancer drug that is highly toxic for renal tissue. This study aimed to evaluate the protective effect of alcoholic extract of saffron stigma against vincristine renal toxicity in male rats. Methods: A total number of 50 rats were randomly divided into 10 groups. Different doses of VCR (0.25, 0.5 and 0.75mg/kg) and saffron (0.5 and ...
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15 صفحه اولPotent mutagenicity of urethan (ethyl carbamate) gas in Drosophila melanogaster.
Exposure of spermatozoa to urethan (ethyl carbamate) gas induced a high frequency of X-linked recessive lethal mutations detected by the Muller-5 technique in Drosophila melanogaster. and a clear dose response was observed. Mutagenic activity of urethan gas on mature spermatozoa following 1.5 (2.4% mutations per chromosome) and 5.5 hr (5.5%) exposure is approximately equal to that induced by 10...
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ژورنال
عنوان ژورنال: Saudi Journal of Biological Sciences
سال: 2010
ISSN: 1319-562X
DOI: 10.1016/j.sjbs.2009.12.008