The proteasome-ubiquitin pathway in the Schistosoma mansoni egg has development- and morphology-specific characteristics
نویسندگان
چکیده
منابع مشابه
The ubiquitin-proteasome pathway and plant development.
The importance of the ubiquitin-proteasome pathway to cellular regulation in eukaryotes has become increasingly apparent during the last several years. This fact was formally acknowledged recently by the awarding of the 2004 Nobel Prize in Chemistry to Aaron Ciechanover, Avram Hershko, and Irwin Rose for the discovery of ubiquitin-mediated protein degradation. In plants, regulated protein degra...
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این پژوهش با هدف "بررسی وضعیت موجود آموزش عالی مجازی در ایران و راههای توسعه و ارتقای آن " و با روش توصیفی-تحلیلی و پیمایشی صورت پذیرفته است. بررسی اسنادو مدارک موجود در زمینه آموزش مجازی نشان داد تعداد دانشجویان و مقاطع تحصیلی و رشته محل های دوره های الکترونیکی چندان مطلوب نبوده و از نظر کیفی نیز وضعیت شاخص خدمات آموزشی اساتید و وضعیت شبکه اینترنت در محیط آموزش مجازی نامطلوب است.
The Ubiquitin and Proteasome Pathway
The ubiquitination and proteasome degradation pathway is a multistep enzymatic cascade in eukaryotes in which ubiquitin is conjugated via a lysine residue at position 48 to target proteins for destruction. Proteins tagged with lysine 48–linked chains of ubiquitin are marked for degradation in the proteasome enzyme complex (Figure 1). Through this pathway, the cell rids itself of excess and misf...
متن کاملProteomic analysis of Schistosoma mansoni egg secretions.
Schistosomiasis remains a largely neglected, global health problem. The morbid pathology of the disease stems from the host's inflammatory response to parasite eggs trapped in host tissues. Long term host/parasite survival is dependent upon the successful modulation of the acute pathological response, which is induced by egg antigens. In this study, using Multidimensional Protein Identification...
متن کاملThe ubiquitin-proteasome pathway and synaptic plasticity.
Proteolysis by the ubiquitin-proteasome pathway (UPP) has emerged as a new molecular mechanism that controls wide-ranging functions in the nervous system, including fine-tuning of synaptic connections during development and synaptic plasticity in the adult organism. In the UPP, attachment of a small protein, ubiquitin, tags the substrates for degradation by a multisubunit complex called the pro...
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ژورنال
عنوان ژورنال: Molecular and Biochemical Parasitology
سال: 2011
ISSN: 0166-6851
DOI: 10.1016/j.molbiopara.2010.10.005