The potential impact of migraine headache on retinal nerve fiber layer thickness

Abstract Background Migraine is a common, chronic, multifactorial neurovascular disorder. It may result in hypoperfusion of other areas than the brain, as eye. lead to change retinal nerve fiber layers (RNFL) thickness and axonal loss even up severe damage eye structures, including retina with frequent headache attacks. This study aimed quantify RNFL which gives good idea about condition axons ganglion cells migraine patients. Also, detect if there any correlation between these measurements clinical characteristics migraine. Results The was significantly thinner patients compared healthy controls all quadrants both sides ( p value < 0.05). However, no significant difference aura without > intensity negatively correlated inferior r = − 0.342, P 0.031) nasal 0.349, 0.027) on LT side, also positive nausea tolerability RT superior quadrant 0.467, 0.002); 0.322, 0.043), respectively, but found disability, attacks duration, disease duration frequency Conclusion main conclusion our work that affected comparison controls, were impact aura, severity, frequency, or thickness.