The pleiotropic effects of paricalcitol: Beyond bone-mineral metabolism
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چکیده
منابع مشابه
Effects of cirrhosis on bone mineral density and bone metabolism.
OBJECTIVE The present study was undertaken to examine the correlation between the severity of liver disease and the presence and severity of bone disease in patients with hepatic cirrhosis. MATERIALS AND METHODS Between January 2005 and February 2006, 40 patients with cirrhosis and 22 healthy controls were enrolled in a cross-sectional study. All subjects underwent standard laboratory testing...
متن کاملBone and Mineral Metabolism
Background: Evidence suggests that vitamin D status in adults is positively associated with calcium absorption fraction and inversely associated with serum PTH. The objective of this study was to evaluate the relationships among vitamin D status, PTH, and calcium absorption in midpubertal boys and girls. Methods: Calcium absorption was measured by using a stable isotope method in 93 young adole...
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statement of problem: glucocorticoid-induced osteoporosis is characterized by a decrease in osteoblast numbers and a marked impairment of new bone formation. purpose: the ain of present study was to evaluate the effect of methylprednisolone acetate on bone metabolism and bone mineral density in rats. materials and methods: eighteen male sprague dawley rats (8 weeks old, weighting 180 gm) were r...
متن کاملRegulation of Bone Metabolism
Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...
متن کاملAchievement of recommended treatment targets for bone and mineral metabolism in haemodialysis patients using paricalcitol: an observational study.
OBJECTIVE Secondary hyperparathyroidism (SHPT) is a common problem among patients with chronic kidney disease (CKD) on haemodialysis. This study was conducted to assess the use, effectiveness and safety of intravenous paricalcitol in haemodialysis patients with various degrees of SHPT. MATERIAL AND METHODS This observational, multicentre, prospective study was conducted in 14 Swedish dialysis...
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ژورنال
عنوان ژورنال: Nefrología (English Edition)
سال: 2016
ISSN: 2013-2514
DOI: 10.1016/j.nefroe.2016.02.006