منابع مشابه
The platelet microparticle proteome.
Platelet-derived microparticles are the most abundant type of microparticle in human blood and contribute to many biologically significant processes. Here, we report the first proteomic analysis of microparticles generated from activated platelets. Using 1D SDS-PAGE and liquid chromatography coupled to a linear ion trap mass spectrometer, the identification of 578 proteins was accomplished usin...
متن کاملThe Human Plasma Proteome
The human plasma proteome holds the promise of a revolution in disease diagnosis and therapeutic monitoring provided that major challenges in proteomics and related disciplines can be addressed. Plasma is not only the primary clinical specimen but also represents the largest and deepest version of the human proteome present in any sample: in addition to the classical “plasma proteins,” it conta...
متن کاملExploring the human plasma proteome.
The Human Proteome Organization (HUPO) has launched several major initiatives to explore the proteomes of liver, brain, and plasma and to generate informatics standards and large-scale antibody production. This issue of PROTEOMICS presents 28 papers from the pilot phase of the Human Plasma Proteome Project. The papers represent a combination of collaborative analyses of HUPO PPP reference speci...
متن کاملTHE HUPO Human Plasma Proteome Project.
The Human Proteomics Organization (HUPO) Human Plasma Proteome Project (PPP) is a prominent example of the inherently collaborative nature of the overall community effort to characterize the proteome of humans in health and disease. The PPP Pilot Phase, called "Exploring the Human Plasma Proteome", engaged 55 laboratories, four technical committees, and vendors and sponsors on an international ...
متن کاملCalorimetric analysis of the plasma proteome.
The plasma proteome is a complex mixture of more than 3,000 proteins that has routinely been exploited by physicians for clinical diagnostic assays. More recently, the low-abundance region of the proteome has been examined for potential biomarkers of disease. A calorimetric assay has been developed that exploits a new physical basis with which to interrogate the plasma proteome. This article pr...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.670.6