The Phenotype/Genotype Correlation of Lactase Persistence among Omani Adults
نویسندگان
چکیده
منابع مشابه
The Phenotype/Genotype Correlation of Lactase Persistence among Omani Adults.
OBJECTIVE To examine the correlation of lactase persistence phenotype with genotype in Omani adults. METHODS Lactase persistence phenotype was tested by hydrogen breath test in 52 Omani Adults using the Micro H2 analyzer. Results were checked against genotyping using direct DNA sequencing. RESULTS Forty one individuals with C/C-13910 and T/T-13915 genotypes had positive breath tests (≥20 pp...
متن کاملEvolution of Lactase Persistence
Though humans are known to lose lactase ability post-weaning, some people maintain lactase production into adulthood, a condition known as lactase persistence. Global distribution patterns of lactase persistency are inconsistent; the condition is much more prevalent in some populations than others. Using results across independent studies, the existence of such a phenomenon can be attributed to...
متن کاملPrevalence of the metabolic syndrome among Omani adults.
OBJECTIVE To estimate the prevalence of the metabolic syndrome by age and sex in the Omani population as defined by the third report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III [ATP III]) of North America. RESEARCH DESIGN AND METHODS We analyzed data from a cross-sectional sur...
متن کاملMolecular Genetics of Lactase Persistence
This thesis is based on the following original articles, which are referred to in the text by their Roman numerals. In addition, some unpublished data are presented Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-phlorizin hydrolase gene. Identification of a variant associated with adult-type hypolactasia. Transcriptional regul...
متن کاملThe Origins of Lactase Persistence in Europe
Lactase persistence (LP) is common among people of European ancestry, but with the exception of some African, Middle Eastern and southern Asian groups, is rare or absent elsewhere in the world. Lactase gene haplotype conservation around a polymorphism strongly associated with LP in Europeans (-13,910 C/T) indicates that the derived allele is recent in origin and has been subject to strong posit...
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ژورنال
عنوان ژورنال: Oman Medical Journal
سال: 2013
ISSN: 1999-768X,2070-5204
DOI: 10.5001/omj.2013.98