The Pathomorphology of Malignant Catarrhal Fever

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Malignant Catarrhal Fever

MCF is defined by the recognition of characteristic lymphoid cell accumulations in non-lymphoid organs, vasculitis, and T-lymphocyte hyperplasia in lymphoid organs, and can be caused by either of two gamma-herpesviruses. The alcelaphine herpesvirus-1 (AIHV-1), the natural host of which, the wildebeest, is infected inapparently, causes the disease in cattle in regions of Africa and various rumin...

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Malignant catarrhal fever.

Malignant catarrhal fever is briefly reviewed and recent findings are described. Initially the disease was observed as a disease of cattle in Europe where, although no cause could be identified, circumstantial evidence implicated sheep as a source of infection and it was thus designated 'sheep-associated' malignant catarrhal fever. Subsequently the disease was observed in Africa where it became...

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Malignant catarrhal fever (MCF)

Despite the severe pathological changes that occur in animals affected by MCF the pathogenesis remains to be fully elucidated. What is certain, however, is that the lesions do not arise through direct virus-induced cytopathology as there is no evidence of herpesvirus cytopathic effects and very little evidence of viral antigen or nucleic acid can be found in them. Consequently, numerous authors...

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Malignant Catarrhal Fever

Malignant Catarrhal Fever (MCF), a fatal disease of a large number of different ruminants, is caused by infection with either a blue or black wildebeest-associated alcephaline herpesvirus 1 (AlHV-1) or the sheep-associated ovine herpes virus 2 (OvHV-2).Wildebeest and sheep are the natural hosts of these viruses respectively. Both these forms of MCF are of great economic importance, particularly...

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Malignant catarrhal fever: a review.

Malignant catarrhal fever (MCF) is a fatal lymphoproliferative disease of cattle and other ungulates caused by the ruminant gamma-herpesviruses alcelaphine herpesvirus 1 (AlHV-1) and ovine herpesvirus 2 (OvHV-2). These viruses cause inapparent infection in their reservoir hosts (wildebeest for AlHV-1 and sheep for OvHV-2), but fatal lymphoproliferative disease when they infect MCF-susceptible h...

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ژورنال

عنوان ژورنال: Veterinary Pathology

سال: 1980

ISSN: 0300-9858,1544-2217

DOI: 10.1177/030098588001700108