The Oxytricha trifallax Mitochondrial Genome
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منابع مشابه
The Oxytricha trifallax Mitochondrial Genome
The Oxytricha trifallax mitochondrial genome contains the largest sequenced ciliate mitochondrial chromosome (~70 kb) plus a ~5-kb linear plasmid bearing mitochondrial telomeres. We identify two new ciliate split genes (rps3 and nad2) as well as four new mitochondrial genes (ribosomal small subunit protein genes: rps- 2, 7, 8, 10), previously undetected in ciliates due to their extreme divergen...
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The macronuclear genome of the ciliate Oxytricha trifallax displays an extreme and unique eukaryotic genome architecture with extensive genomic variation. During sexual genome development, the expressed, somatic macronuclear genome is whittled down to the genic portion of a small fraction (∼5%) of its precursor "silent" germline micronuclear genome by a process of "unscrambling" and fragmentati...
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We propose construction of a BAC library for the germline micronuclear genome (MIC) of the ciliate protist Oxytricha trifallax (recently renamed Sterkiella histriomuscorum; alveolate; class Spirotrichia). This library will primarily be used as a tool to characterize the structure and function of the ciliate micronucleus and its relationship to that of the somatic macronucleus, rather than for c...
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Ciliates have two different types of nuclei per cell, with one acting as a somatic, transcriptionally active nucleus (macronucleus; abbr. MAC) and another serving as a germline nucleus (micronucleus; abbr. MIC). Furthermore, Oxytricha trifallax undergoes extensive genome rearrangements during sexual conjugation and post-zygotic development of daughter cells. These rearrangements are necessary b...
متن کاملTranscription-independent functions of an RNA polymerase II subunit, Rpb2, during genome rearrangement in the ciliate, Oxytricha trifallax.
The RNA polymerase II (Pol-II) holoenzyme, responsible for messenger RNA production, typically consists of 10-12 subunits. Our laboratory previously demonstrated that maternally deposited, long, noncoding, template RNAs are essential for programmed genome rearrangements in the ciliate Oxytricha trifallax. Here we show that such RNAs are bidirectionally transcribed and transported to the zygotic...
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2011
ISSN: 1759-6653
DOI: 10.1093/gbe/evr136