THE OXIDATION OF p-AMINOBENZOIC ACID AND ANTHRANILIC ACID BY SPECIFICALLY ADAPTED ENZYMES OF A SOIL BACILLUS

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

THE OXIDATION OF p-AMINOBENZOIC ACID AND ANTHRANILIC ACID BY SPECIFICALLY ADAPTED ENZYMES OF A SOIL BACILLUS

1. A soil bacillus has been isolated capable of developing specific adaptive enzymes which oxidize PABA apparently to carbon dioxide, water, and ammonia. A few related compounds which, however, do not give the diazo reaction are similarly attacked. 2. This bacillus is also capable of developing analogous but apparently independent adaptive enzymes specifically directed against anthranilic acid,...

متن کامل

Mechanism of competitive inhibition of p-aminobenzoic acid oxidation by p-aminosalicylic acid.

The proposed mechanism(s) associated with the inhibition of essential metabolic reactions by various compounds has received a great deal of attention in recent years, since antimetabolites have proved useful in several chemotherapeutic areas and in studying various metabolic reactions. The significance of p-aminobenzoic acid in microbial nutrition was first emphasized when Woods (1940) and Wood...

متن کامل

Kinetics of the oxidation of p-aminobenzoic acid catalyzed by horseradish peroxidase compounds I and II.

The kinetics of p-aminobenzoic acid oxidation catalyzed by horseradish peroxidase Compounds I and II was investigated intensively as a function of pH at 25 degrees in aqueous solutions of ionic strength 0.11. All of the rate data were collected from single turnover experiments involving reactions of a single enzyme compound. In reactions of both compounds, deviations from first order behavior w...

متن کامل

Effect of structurally related compounds on the oxidation of p-aminobenzoic acid by Pseudomonas fluorescens.

The realization that p-aminobenzoic acid is essential as a growth factor has stimulated extensive research in the field of antagonists of this essential metabolite. Woods (1940) and Woods and Fildes (1940) reported that yeast contained a substance, identified as p-aminobenzoic acid, that could protect it against the growth inhibiting action of sulfanilamide. Youmans et al. (1947) reported the t...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Experimental Medicine

سال: 1943

ISSN: 1540-9538,0022-1007

DOI: 10.1084/jem.78.4.255