The other side of kinetochore fibers
نویسندگان
چکیده
منابع مشابه
The other side of kinetochore fibers
The other side of kinetochore fibers n page 671, Khodjakov et al. uncover a new mechanism of spindle morphogenesis that involves the capture of microtubule minus ends. In the established model of spindle formation in vertebrate cells, spindle microtubule minus ends are focused at spindle poles in association with centrosome-nucleated microtubules. Kinetochore O fibers, which pull chromosomes to...
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It is now clear that a centrosome-independent pathway for mitotic spindle assembly exists even in cells that normally possess centrosomes. The question remains, however, whether this pathway only activates when centrosome activity is compromised, or whether it contributes to spindle morphogenesis during a normal mitosis. Here, we show that many of the kinetochore fibers (K-fibers) in centrosoma...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2003
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1605iti1