The onset of liver glycogen synthesis in fasted-refed lean and genetically obese (fa/fa) rats
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چکیده
منابع مشابه
The onset of liver glycogen synthesis in fasted-refed rats. Effects of streptozocin diabetes and of peripheral insulin replacement.
The mechanism of liver glycogen synthesis after refeeding has been investigated in diabetic rats, diabetic insulin-treated rats, and in control rats fasted for 48 h. The accumulation of liver glycogen was the same in diabetic rats and in control rats after 2 h of feeding, but did not proceed any further in the diabetic group during the next 2 h. Insulin-treated diabetic rats synthesized five ti...
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To determine whether the antilipogenic actions of insulin-induced gene 1 (insig-1) demonstrated in cultured preadipocytes also occur in vivo, we infected Zucker diabetic fatty (ZDF) (fa/fa) rats, with recombinant adenovirus containing insig-1 or -2 cDNA. An increase of both proteins appeared in their livers. In control ZDF (fa/fa) rats infected with adenovirus containing the beta-galactosidase ...
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Many hypothalamic nuclei are involved in the regulation of food intake and energy homeostasis. An ultrastructural investigation of the hypothalamic ventromedial nucleus (VMN), a hypothetical "satiety centre" was performed to explore the morphological basis of altered feeding behaviour of old rats in an experimental model of fasting/refeeding. Young (5 months old, n=12) and old (24 months old, n...
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The effect of moderate hyperleptinemia (∼20 ng/ml) on liver and skeletal muscle glycogen metabolism was examined in Wistar rats. Animals were studied ∼90 h after receiving recombinant adenoviruses encoding rat leptin (AdCMV-leptin) or β-galactosidase (AdCMV-βGal). Liver and skeletal muscle glycogen levels in the fed and fasted (18 h) states were similar in AdCMV-leptin- and AdCMV-βGal-treated r...
متن کاملGlycogen synthesis in the perfused liver of starved rats.
identical with the elongation factors of the supernatant, are present in the ribosomal fraction. These factor(s), presumably, are involved in initiation: however, further investigation is required to elucidate this point. Moreover, preliminary results indicate that a fraction with stimulatory activity similar to that described above can be removed from ribosomes with 0.25Marmmonium chloride. Th...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1987
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00274223