The Neuroprotective Effect of Pyrroloquinoline Quinone on Traumatic Brain Injury
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چکیده
منابع مشابه
The Effect of Pyrroloquinoline Quinone on the Expression of WISP1 in Traumatic Brain Injury
WISP1, as a member of the CCN4 protein family, has cell protective effects of promoting cell proliferation and inhibiting cell apoptosis. Although some studies have confirmed that WISP1 is concerned with colon cancer and lung cancer, there is little report about the influence of WISP1 in traumatic brain injury. Here, we found that the expression of WISP1 mRNA and protein decreased at 3 d and th...
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Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality in young adults and children, and is a leading public health problem worldwide. In TBI, neurological impairment is caused by immediate brain tissue disruption (primary injury) and post‑injury cellular and molecular events (secondary injury) that exacerbate the primary neurological insult. However, the destructi...
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Head trauma is a common event that often causes traumatic brain injury (TBI). Following the acute mechanical insult, TBI evolves over the ensuing minutes and days. Understanding the secondary factors that contribute to TBI might suggest therapeutic strategies to reduce the long-term consequences of brain trauma. To assess secondary factors that contribute to TBI, we studied a fluid percussion i...
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ژورنال
عنوان ژورنال: Journal of Neurotrauma
سال: 2012
ISSN: 0897-7151,1557-9042
DOI: 10.1089/neu.2011.1882