The multiple functions of plant serine protease inhibitors
نویسندگان
چکیده
منابع مشابه
Diverse Clinical Functions of Serine Protease and Its Inhibitors
Serine protease performs normal biological functions in cell. Serine protease are involves in coagulation, inflammation and immunity. Wide variety organisms produce serine proteases including virus, bacteria, animals and plants. Serine proteases are mono-meric enzymes. Serine protease are produced as inactive enzymes called zymogen and transported to other organs where they needed, which are th...
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Unlike most globular proteins, the native form of serine protease inhibitors (serpins) is strained. Previous studies of human alpha(1)-antitrypsin, a prototype plasma serpin, revealed that various unfavorable interactions, such as overpacking of side chains, buried polar groups and cavities, are the structural basis of the strain. The local strain could be relieved by various stabilizing single...
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It has been recognized for many years that the nutritive value and protein digestibility of many plant proteins, particularly those derived from legumes, are very poor unless subjected to cooking or some other form of heat treatment (Liener & Kakade, 1969). This beneficial effect of heat has beem generally attributed, at least in part, to the destruction of a unique class of proteins which have...
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One of the important parts of innate immunity is complement system that occurs in three different ways; the classic, the alternative and the lectin pathway. The four pattern recognition molecules that have been identified till now are Mannose binding lectin (MBL), a component of lectin pathway, and three ficolins (ficolin1,-2 and -3) which compound to the carbohydrates of the cell surface. MBL ...
متن کامل4-Heterocyclohexanone-based inhibitors of the serine protease plasmin.
Three inhibitors that are based upon a 4-heterocyclohexanone nucleus were synthesized and evaluated for activity against the serine protease plasmin. Inhibitors of plasmin have potential as cancer chemotherapeutic agents that act by blocking both angiogenesis and metastasis. Inhibitor 1 has moderate activity against plasmin but shows good selectivity for this enzyme compared to other serine pro...
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ژورنال
عنوان ژورنال: Plant Signaling & Behavior
سال: 2011
ISSN: 1559-2324
DOI: 10.4161/psb.6.7.15504