The miR-608 rs4919510 polymorphism may modify cancer susceptibility based on type
نویسندگان
چکیده
منابع مشابه
Association of miR-608 rs4919510 polymorphism and cancer risk: a meta-analysis based on 13,664 subjects
Single nucleotide polymorphisms (SNPs) in MicroRNAs (miRNAs) are involved in the mechanism of carcinogenesis. Several studies have evaluated the association of rs4919510 SNP in miR-608 with cancer susceptibility in different types of cancer, with inconclusive outcomes. To obtain a more precise estimation, we carried out this meta-analysis through systematic retrieval from the PubMed and Embase ...
متن کاملA meta-analysis: Is there any association between MiR-608 rs4919510 polymorphism and breast cancer risks?
OBJECT To combine the data from previously conducted studies about the associations between miR-608 rs4919510 polymorphism (C>G) and breast cancer risks. METHODS According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, we conducted a systematic review of the related literatures searched from PubMed, Embase, Cochrane Library, Web of Science, and ...
متن کاملrs4919510 in hsa-mir-608 Is Associated with Outcome but Not Risk of Colorectal Cancer
BACKGROUND Colorectal cancer is the third most incident cancer and cause of cancer-related death in the United States. MicroRNAs, a class of small non-coding RNAs, have been implicated in the pathogenesis and prognosis of colorectal cancer, although few studies have examined the relationship between germline mutation in the microRNAs with risk and prognosis. We therefore investigated the associ...
متن کاملThe Associations of Single Nucleotide Polymorphisms in miR196a2, miR-499, and miR-608 With Breast Cancer Susceptibility
MicroRNAs (miRNAs) play an important role as regulators of tumor suppressors and oncogenes in cancer-related processes. Single nucleotide polymorphisms (SNPs) in miRNAs have been shown to be relevant to various different cancers, including breast cancer (BC). The aim of this study was to estimate the associations between miRNA-related gene polymorphisms (miR-196a2, miR-499, and miR-608) and the...
متن کاملmiR-124 rs531564 polymorphism influences genetic susceptibility to cervical cancer.
Cervical cancer is the fourth most common cancer among women worldwide. It most frequently results from human papillomavirus (HPV) infection; however, recent evidence suggests that there may be underlying genetic factors, specifically in regions encoding microRNAs, dictating susceptibility to cervical cancer. This study investigated the relationship between the miR-124 rs531564 gene polymorphis...
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ژورنال
عنوان ژورنال: Tumor Biology
سال: 2017
ISSN: 1010-4283,1423-0380
DOI: 10.1177/1010428317703819