THE METABOLISM OF SOME PYRIMIDINES

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15 صفحه اول

Nucleotide Metabolism – Purines and Pyrimidines

Nucleotide metabolism results in the synthesis of the four nucleotides that form DNA. These are further divided in two categories: purines and pyrimidines. Their construction and degradation takes place in a progression of single steps, while different enzymes and cofactors are involved in the process. Beside degradation, there is also a form of reprocessing purine and pyrimidine nucleotides, d...

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Nucleotide Metabolism – Purines and Pyrimidines

Nucleotide metabolism results in the synthesis of the four nucleotides that form DNA. These are further divided in two categories: purines and pyrimidines. Their construction and degradation takes place in a progression of single steps, while different enzymes and cofactors are involved in the process. Beside degradation, there is also a form of reprocessing purine and pyrimidine nucleotides, d...

متن کامل

Nucleotide Metabolism – Purines and Pyrimidines

Nucleotide metabolism results in the synthesis of the four nucleotides that form DNA. These are further divided in two categories: purines and pyrimidines. Their construction and degradation takes place in a progression of single steps, while different enzymes and cofactors are involved in the process. Beside degradation, there is also a form of reprocessing purine and pyrimidine nucleotides, d...

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SYNTHESIS OF 4,4'-BIS-PYRIMIDINES AND SOME RELATED BIS-FUSED PYRIMIDINES

2,2'-Disubstitutedamino-4-4'-bis-pyrimidines (3a-m) have been prepared by linking 2,4-dichloro-6-methyl-5-nitropyrimidine (1) with several diamines and subsequent reaction with suitable amines. Some of these compounds (3c and 3j) which were reduced catalitically, on treatment with nitrous acid, urea in pyridine, and boiling thionyl chloride gave the corresponding bistriazolopyrimidin (6), ...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 1924

ISSN: 0021-9258

DOI: 10.1016/s0021-9258(18)85202-4