The Maternal Serum Alpha-Fetoprotein for Congenital Anomalies Screening

Screening examination for maternal, especially serum, is a non-invasive of the fetus’s condition. During pregnancy, screening examinations are performed in women recommended ultrasonography (USG), amniocentesis, or other obstetric interventions. There three markers maternal serum screening: alpha-fetoprotein, human chorionic gonadotropin (hCG), and unconjugated estriol. Maternal alpha-fetoprotein useful aneuploidies neural tube defects. This examination, besides seeing congenital abnormalities, can be used risk pregnancy complications such as placental insufficiency, intrauterine growth restriction, preeclampsia, fetal death. Laboratory methods examining radioimmunoassay microparticle capture enzyme immunoassay.
 Keywords: Screening, Pregnancy, Alpha-Fetoprotein,