The ‘malic’ enzyme in insect blood

Malic Enzyme of Escherichia coli

The TPN+-specitk malic enzyme from Escherichia coli has been purified from malate-grown cells. An approximately loo-fold purified preparation is activated by NH4+ and K+ ions. The enzyme is inhibited by acetyl coenzyme A, oxalacetate, TPNH, and DPNH in an allosteric manner. Glycine at concentration ranges above 0.5 M has been shown to activate the enzyme as well as to desensitize it reversibly ...

Cardiac malic enzyme in Friedreich's disease.

We measured the activity of cytosolic and of mitochondrial malic enzyme in the hearts from 4 patients with Friedreich's disease and from two non-ataxic control subjects. There was a wide variability in the results and the slight overall decreases in both enzyme activities were not considered to be statistically significant. From these and other results, we conclude that deficient mitochondrial ...

Malic Enzyme and Lipogenesis * by Edmund

10 Gershenson, S. I., J. Genet., 28, 297-313 (1933). 11TheYsX . YL-chromosome does not permit a decision as to whether YS and yL can conjoin intrachromosomally, even though this chromosome regularly conjoins with itself in Y8X.YL/O spermatocytes (Fig. 3i). Here "Ys" denotes with certainty only the Y8-fertility genes, for the "Ys" element itself (Fig. 3h) is morphologically unlike the short arm ...

Limited proteolysis of maize NADP-malic enzyme.

The incubation of maize malic enzyme at 37 degrees C with trypsin at a ratio of 150:1 of malic enzyme to trypsin caused rapid and complete inactivation of enzyme activity. The inactivation was caused by fairly specific cleavage of the enzyme monomer (62 kDa) into 40 kDa and 20 kDa fragments. The intensity of 40 kDa band increased with the time of treatment of enzyme with trypsin from 2 to 30 mi...

Studies on Malic Enzyme from Hymenolepis Diminuta