The Lysis of Intravascular Thrombi in Rabbits with Human Plasmin (Fibrinolysin)
نویسندگان
چکیده
منابع مشابه
The lysis of intravascular thrombi in rabbits with human plasmin (fibrinolysin).
Streptokinase produces it-s lytic effect by activation of a profibrinolysin usually called plasminogen. Many attempt-s have been made to isolate this latter material for investigation without consistent success.#{176}’ ‘#{176} A new method for preparation of this material (plasminogen)’t ‘ 12 has recently been reported. In vivo stu lies of activated plasminogen (plasmin) in dogs and rabhit-&3 h...
متن کاملStudies on the production of intravascular thrombi and their treatment with fibrinolysin.
IT HAS been shown in experimental animals that the human fibrinolytic enzyme (plasminogen activated with streptokinase) will dissolve fresh intravascular thrombi." Fibrinolytic agents are also undergoing an extensive clinical trial and the preliminary reports which have appeared*" have suggested that this type of therapy will be of value in the management of thrombo-embolic disorders. Variation...
متن کاملFibrinolysin ( Plasmin ) Therapy in Acute Deep Thrombophlebitis
THE magnlitude of the literature dealing with deep thrombophlebitis of the lower extremities and its complications reflects not onily the interest that this disorder commands among physicians but also the extensive controversy that it has generated. Controversy surrounds even such fundamental problems as the pathogenesis of venous thromboembolism, the natural course of the process, and the adeq...
متن کاملFibrinolysin ( Plasmin ) Therapy in Acute Deep
THE magnlitude of the literature dealing with deep thrombophlebitis of the lower extremities and its complications reflects not onily the interest that this disorder commands among physicians but also the extensive controversy that it has generated. Controversy surrounds even such fundamental problems as the pathogenesis of venous thromboembolism, the natural course of the process, and the adeq...
متن کاملEffects of intravenous administration of fibrinolysin (plasmin) in man.
The potentiality of dissolving clots has aroused great interest in fibrinolysin (plasmin) as a therapeutic agent in thromboembolism. In this paper the effects of intravenous administration of purified fibrinolysin in man are reported, with special emphasis upon systemic toxicity and alterations in clotting factors and fibrinolytic activity. This information is necessary for the evaluation of th...
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ژورنال
عنوان ژورنال: Blood
سال: 1954
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v9.4.310.310