The iodination sites of bovine thyrotropin.

Molecular cloning of bovine thyrotropin-releasing hormone receptor gene.

The genomic DNA encoding bovine Thyrotropin-Releasing Hormone Receptor (TRHR) was isolated from a bovine (Holstein) genomic library. Using PCR fragments of bovine candidate TRHR Transmembrane domain (TMD-III-IV) and C-terminus domain of mouse TRHR cDNA as probes, 9 x 10(5) plaques were screened to obtain several clones each containing the N-terminus or C-terminus domain. The bovine TRHR gene en...

Studies of In-Vitro Amlodipine and Arsenic Displacement Interaction at Binding Sites of Bovine Serum Albumin

In this study, the binding of amlodipine (a Ca ++ channel Blocker) and arsenic (metalloid) to bovine serum albumin (BSA) was studied by equilibrium dialysis(ED) method in order to have an insight into their binding chemistry to BSA. Free amlodipine concentration was increased due to addition of arsenic which reduced the binding of the compounds to BSA. However, the free fraction was not increa...

Novel IgA antibody to bovine thyrotropin in a healthy man.

Bovine serum hormone concentrations after thyroprotein and thyrotropin releasing hormone.

Twenty-four Holstein heifers were assigned randomly to one of four t reatment groups to be given: 1) thyroprote in (TP) for 6 days; 2) casein for 6 days; 3) TP for 27 days; or 4) casein for 27 days. Thyrotropin releasing hormone (TRH, 33.3 /~g/100 kg BW) was given at 1030 and 1330 hr on day 6 or 33 to heifers treated for 6 or 27 days, respectively. Prior to TRH treatment , serum thyroxine (T4) ...

The Therapeutic Effect of Thyrotropin Releasing Hormone in Amyotrophic Sclerosis

Although the issue has not yet been fully resolved, there is reason to believe that TRI-I may have a trophic effect on the normal motoneuron and may transien­ tly improve the neurologic deficit in ALS. Since ALS is not a simple TRI-I deficiency disease, this improvement probably occurs via a secondary mecha -nism-possibly another neurotransmitter. It is uncertain at this time whether this effec...