The Intracellular Growth of Fowl-Plague Virus
نویسندگان
چکیده
منابع مشابه
Influenza virus M2 protein ion channel activity stabilizes the native form of fowl plague virus hemagglutinin during intracellular transport.
The influenza A/fowl plague virus/Rostock/34 hemagglutinin (HA), which is cleaved intracellularly and has a high pH threshold (pH 5.9) for undergoing its conformational change to the low-pH form, was expressed from cDNA in CV-1 and HeLa T4 cells in the absence of other influenza virus proteins. It was found, by biochemical assays, that the majority of the HA molecules were in a form indistingui...
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A case of human fowl plague keratoconjunctivitis occurred after accidental laboratory exposure. The conjunctivitis was characterised by follicle formation and a mucopurulent discharge, and ran a self-limiting course over two weeks. The keratitis was of an unusual type and consisted of small intraepithelial opacities, which appeared after one week and resolved completely over the next three week...
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The rate of incorporation of 5-fluorouracil into complementary strands of replicating RNA of fowl plague virus (FPV) has been studied. The efficiency of incorporation was estimated by determination of the reversion frequency in s-mutants with known types of base transitions in the RNA of the virus particle. It was established that maximum incorporation of 5-fluorouracil into progeny virus parti...
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During the formation of incomplete fowl plague virus, normal amounts of viral compounds are synthesized. The S-antigen, however, cannot be demonstrated within the cytoplasm in appreciable amounts by fluorescent antibody. The oligonucleotide pattern and the specific radioactivity of the ribonucleic acid (RNA) of incomplete forms are almost identical with those of standard virus. In contrast to c...
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We describe retrovirus particles carrying the fowl plague virus (FPV) hemagglutinin (HA). When expressed in cells providing Moloney murine leukemia virus (MoMLV) Gag and Pol proteins and a lacZ retroviral vector, FPV HA was found to be efficiently expressed, correctly processed, and stably incorporated into retroviral particles. HA-bearing retroviruses were infectious with a wide host range and...
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ژورنال
عنوان ژورنال: Journal of General Microbiology
سال: 1951
ISSN: 0022-1287
DOI: 10.1099/00221287-5-2-279