The importance of molecular diagnostics for infectious diseases in low-resource settings
نویسندگان
چکیده
منابع مشابه
Molecular Genomic Approaches to Infectious Diseases in Resource-Limited Settings
Only half a century after the landmark discovery of the double helix structure of DNA, the human genome was sequenced and a new era of biomedical research was ushered in [1]. Parallel advances in comparative genomics, genetics, highthroughput biochemical techniques, and bioinformatics have provided researchers in wealthy nations with a repertoire of tools to analyze the sequence and functions o...
متن کاملMolecular diagnostics of infectious diseases.
Over the past several years, the development and application of molecular diagnostic techniques has initiated a revolution in the diagnosis and monitoring of infectious diseases. Microbial phenotypic characteristics, such as protein, bacteriophage, and chromatographic profiles, as well as biotyping and susceptibility testing, are used in most routine laboratories for identification and differen...
متن کاملMolecular Diagnostics of Infectious Diseases
In DNA-based diagnostics, the polymerase chain reaction (PCR) is the most widely used DNA amplification method. To enable both sensitive and specific detection of agents causing infectious diseases, the PCR needs to be combined with methods to prepare the clinical sample containing the genetic material of the pathogen. Furthermore, methods for detection and DNA sequence analysis of the PCR ampl...
متن کاملMolecular diagnostics of infectious diseases.
PURPOSE OF REVIEW The purpose of this article is to review the molecular methods commonly used in medical microbiology as well as to update the clinician as to newer molecular technologies that show promise in the identification of microorganisms as well as evaluation of the presence of virulence factors and antibiotic resistance determinants. RECENT FINDINGS Numerous molecular assays have be...
متن کاملMolecular markers for resistance against infectious diseases of economic importance
Huge livestock population of India is under threat by a large number of endemic infectious (bacterial, viral, and parasitic) diseases. These diseases are associated with high rates of morbidity and mortality, particularly in exotic and crossbred cattle. Beside morbidity and mortality, economic losses by these diseases occur through reduced fertility, production losses, etc. Some of the major in...
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ژورنال
عنوان ژورنال: Nature Reviews Microbiology
سال: 2021
ISSN: 1740-1526,1740-1534
DOI: 10.1038/s41579-021-00598-5