The impact of the Factor V Leiden mutation on pregnancy
نویسندگان
چکیده
منابع مشابه
The impact of the factor V Leiden mutation on pregnancy.
A resistance to the anticoagulant activity of activated protein C (APC), most frequently due to a point mutation in the Factor V gene (the Leiden mutation), represents the most common genetic cause of thrombophilia. The Leiden mutation has been significantly related to pregnancy complications associated with hypercoagulation, e.g. deep vein thrombosis during pregnancy (8-fold increased risk), p...
متن کاملFactor V Leiden mutation and its impact on pregnancy complications.
OBJECTIVE The aim of this prospective study was to find the association between the factor V Leiden mutation and adverse pregnancy outcomes. METHODS This study is an analysis of a prospective observational study of the frequency of placenta-mediated complications of factor V Leiden mutation carriers. We compared pregnancy outcomes of 11 women with a heterozygous form of the factor V Leiden mu...
متن کاملFactor V Leiden mutation in pregnancy.
Normal maternal adaptation to pregnancy significantly increases the risk for thrombus formation. Inherited thrombophilias further increase risk for deep venous thrombosis and adverse outcome in pregnancy. Factor V Leiden mutation is the most common inherited thrombophilia, occurring in approximately 5% of the White and 1% of the Black populations. Nurses should be knowledgeable about screening ...
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this study investigated the impact of explicit instruction of morphemic analysis and synthesis on the vocabulary development of the students. the participants were 90 junior high school students divided into two experimental groups and one control group. morphological awareness techniques (analysis/synthesis) and conventional techniques were used to teach vocabulary in the experimental groups a...
15 صفحه اولRecurrent Pregnancy Loss in a Subject with Heterozygote Factor V Leiden Mutation; a Case Report
Recurrent pregnancy loss is usually defined as the loss of two or more consecutive pregnancies before 20 weeks of gestation, which occurs in approximately 5% of reproductive-aged women. It has been suggested that women with thrombophilia have an increased risk of pregnancy loss and other adverse pregnancy outcomes. Thrombophilia is an important predisposition to blood clot formation and is cons...
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ژورنال
عنوان ژورنال: Human Reproduction Update
سال: 2000
ISSN: 1355-4786,1460-2369
DOI: 10.1093/humupd/6.3.301