The impact of Tegillarca granosa extract haishengsu on HL-60 cell
نویسندگان
چکیده
منابع مشابه
The impact of Tegillarca granosa extract haishengsu on HL-60 cell
Haishengsu (Hss) is a purified protein from Tegillarca granosa that has been used as a traditional Chinese medicine to treat cancer for more than a century. In this study, we observed the impact of Haishengsu (Hss) on the proliferation and differentiation of HL-60 cells in the leukemic cell line by taking tretinoin and AS2O3 as a positive control and making a comparative analysis between the ef...
متن کاملTegillarca granosa extract Haishengsu (HSS) suppresses expression of mdr1, BCR/ABL and sorcin in drug-resistant K562/ADM tumors in mice.
PURPOSE To evaluate the effect of Haishengsu (HSS), a protein extract from Tegillarca granosa, on multidrug-resistance genes mdr1, BCR/ABL and sorcin in transplanted tumors. MATERIAL/METHODS Mice were inoculated subcutaneously with a drug resistant leukemia cell line K562/ADM. Tumor-bearing animals were divided into control, adriamycin, HSS and combination therapy (adriamycin plus HSS) groups...
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ژورنال
عنوان ژورنال: Open Medicine
سال: 2015
ISSN: 2391-5463
DOI: 10.1515/med-2015-0048