منابع مشابه
Hypercalcemia of Malignancy
CASE STUDY A 60-year-old man initially presented with pain in the right upper quadrant in October 2010. A computed tomography (CT) scan of the abdomen pelvis completed at that time showed a mass at the junction of the body and tail of the pancreas and multiple large liver lesions. A CT-guided liver biopsy revealed low-grade neuroendocrine carcinoma. The patient was initially started on systemic...
متن کاملHumoral Hypercalcemia of Malignancy
Secretion by tumor cells of circulating bone-resorbing factors may frequently underlie the hypercalcemia that occurs in patients with malignancy. Efforts to identify the responsible mediators have been hampered by a lack of available human tumor cell systems suitable for study of the pathogenesis of the humoral hypercalcemia syndrome. We have established a transitionalcell carcinoma (TCC) line ...
متن کاملHypercalcemia of malignancy: Part II.
Oncology nurses are responsible for the ongoing assessment of hypercalcemia, including reviewing laboratory findings as well as evaluating patient symptomatology. Abnormal serum creatinine, calcium, electrolytes, magnesium, and phosphate levels and symptoms such as constipation, lethargy, and weakness may alert clinicians to problems with this oncologic emergency. Resolution of hypercalcemia is...
متن کاملHypercalcemia of malignancy: Part I.
Digital Object Identifier: 10.1188/04.CJON.209-210 Hypercalcemia is a metabolic condition that occurs when the serum calcium level rises above the normal range of 9–11 mg/dl (Myers, 2001; Smith, 2000). It is a complex metabolic oncologic emergency that can be life threatening. This column is the first of a two-part series about hypercalcemia of malignancy (HCM). Part I focuses on the pathophysi...
متن کاملTumor products and the hypercalcemia of malignancy.
Introduction One of the most interesting aspects of the hypercalcemia of malignancy is that it is unlikely that the hypercalcemia is due to the secretion by the tumor cells of one gene product which causes osteoclastic bone resorption and hypercalcemia, but rather that multiple tumor products work in concert on bone and kidney to overwhelm the normal compensatory mechanisms which guard calcium ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1987
ISSN: 0085-2538
DOI: 10.1038/ki.1987.21