The hazards of interrupting anticoagulation therapy in atrial fibrillation
نویسندگان
چکیده
منابع مشابه
The hazards of interrupting anticoagulation therapy in atrial fibrillation.
Atrial fibrillation (AF) is the most commonly encountered clinical arrhythmia and is associated with a substantial burden of morbidity (mainly thrombo-embolism) and mortality. Vitamin K antagonists such as warfarin are highly effective for the prevention of stroke and systemic embolism in patients with AF, but their use is hampered by multiple food and drug interactions, the need for routine co...
متن کاملInterrupting anticoagulation in patients with nonvalvular atrial fibrillation.
Three target-specific oral anticoagulants (TSOACs)-dabigatran, rivaroxaban, and apixaban-have been approved by the FDA to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation; however, no agents are currently approved to reverse the anticoagulant effects of these TSOACs in cases of active bleeding. This review discusses the benefits and risks of these...
متن کاملAnticoagulation in Atrial Fibrillation
Atrial fibrillation (AF) is the most commonly occurring arrhythmia. An antithrombotic agent is considered mandatory as part of the management in most patients with AF. It has been conclusively demonstrated that long-term anticoagulation therapy can significantly reduce the risk of stroke in patients with non-valvular AF. While vitamin K antagonists (VKAs) such as warfarin are highly effective, ...
متن کاملAnticoagulation in atrial fibrillation
Atrial fibrillation (AF) affects approximately 300,000 Australians and has a growing prevalence. It is associated with high rates of death and disability. The majority of people with AF are eligible to be treated with anticoagulant medications, but practice is often inadequate, leaving many people at risk of stroke. Until recently, the only antithrombotics available to prevent stroke in people ...
متن کاملTrends in Oral Anticoagulation Therapy Among Korean Patients With Atrial Fibrillation: The KORean Atrial Fibrillation Investigation
BACKGROUND AND OBJECTIVES Anticoagulation with vitamin K antagonists (VKAs) such as warfarin provides effective stroke prophylaxis in patients with atrial fibrillation (AF). We conducted a large multicenter survey of Korean patients with AF to determine trends in VKA use. SUBJECTS AND METHODS Eligible patients were adults with AF that had been prescribed VKAs. Medical records from a total of ...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2012
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/ehs032