The Gastrointestinal Pharmacology of Cannabinoids: Focus on Motility

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The gastrointestinal pharmacology of cannabinoids: focus on motility.

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The plant Cannabis has been known for centuries to be beneficial in a variety of gastrointestinal diseases, including emesis, diarrhea, inflammatory bowel disease and intestinal pain. delta9-tetrahydrocannabinol, the main psychotropic component of Cannabis, acts via at least two types of cannabinoid receptors, named CB1 and CB2 receptors. CB1 receptors are located primarily on central and perip...

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Dronabinol (Delta 9-tetrahydocannabinol, THC), the main source of the pharmacological effects caused by the use of cannabis, is an agonist to both the CB1 and the CB2 subtype of cannabinoid receptors. It is available on prescription in several countries. The non-psychotropic cannabidiol (CBD), some analogues of natural cannabinoids and their metabolites, antagonists at the cannabinoid receptors...

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ژورنال

عنوان ژورنال: Pharmacology

سال: 2012

ISSN: 0031-7012,1423-0313

DOI: 10.1159/000339072