The GALNT14 Genotype Predicts Postoperative Outcome of Pancreatic Ductal Adenocarcinoma
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چکیده
منابع مشابه
GALNT14 Genotype Predicts Postoperative Outcome of Stage III Colorectal Cancer With Oxaliplatin as Adjuvant Chemotherapy
Adjuvant oxaliplatin-based chemotherapy is widely used for stage III colorectal cancer (CRC) after curative surgery. CRC is a molecularly heterogeneous disease, and our current knowledge of therapeutic response-related genetic factors remains limited. N-acetylgalactosaminyltransferase 14 (GALNT14)-rs9679162 genotype is a prognostic predictor for chemotherapy response in advanced hepatocellular ...
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Casitas B-lineage lymphoma b (Cbl-b) is a ubiquitin-protein ligase and a signal transducing adaptor protein involved in immune regulation, and it may be involved in the development and progression of cancer. We investigated the association between Cbl-b expression and prognosis in patients with resectable pancreatic ductal adenocarcinoma (PDAC). The clinicopathological characteristics and survi...
متن کاملExpression of amphiregulin predicts poor outcome in patients with pancreatic ductal adenocarcinoma
BACKGROUND The validation of novel diagnostic, prognostic and predictive biomarkers in cancer is crucial for optimizing the choice and efficacy of personalized therapies. The aim of this study was to determine the epidermal growth factor receptor (EGFR), epidermal growth factor receptor variant III (EGFRvIII) and amphiregulin (AREG) protein expression levels and to evaluate the prognostic signi...
متن کاملCorrigendum: Decreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
In the original version of this Article, there was a typographical error in Affiliation 1 which was incorrectly listed as ' This error has now been corrected in the PDF and HTML versions of the Article. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons lice...
متن کاملDecreased LKB1 predicts poor prognosis in Pancreatic Ductal Adenocarcinoma
Liver kinase B1 (LKB1) has been identified as a critical modulator involved in cell proliferation and polarity. The purpose of the current study was to characterize the expression pattern of LKB1 and assess the clinical significance of LKB1 expression in pancreatic ductal adenocarcinoma (PDAC) patients. LKB1 mRNA expression which was analyzed in 32 PDAC lesions and matched non-tumor tissues, wa...
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ژورنال
عنوان ژورنال: Journal of Clinical Medicine
سال: 2019
ISSN: 2077-0383
DOI: 10.3390/jcm8122225