The First Observation of Homozygous Hemoglobin S-Alpha Thalassemia Disease and Two Types of Sickle Cell Thalassemia Disease: (a) Sickle Cell-Alpha Thalassemia Disease, (b) Sickle Cell-Beta Thalassemia Disease

The First Observation of Homozygous Hemoglobin S-alpha Thalassemia Disease and Two Types of Sickle Cell Thalassemia Disease: (a) Sickle Cell-alpha Thalassemia Disease, (b) Sickle Cell-beta Thalassemia Disease.

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

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The First Observation of Homozygous Hemoglobin S.Alpha Thalassemia Disease and Two Types of Sickle Cell Thalassemia Disease : (a) Sickle Cell-Alpha Thalassemia Disease, (b) Sickle Cell-Beta Thalassemia Disease

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

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The First Observation of Homozygous Hemoglobin S . Alpha Thalassemia Disease and Two Types of Sickle Cell

S ICKLE CELL-THALASSEMIA DISEASE is known to be a severe or moderately severe type of congenital hemolytic anemia. The clinical and hematologic pictures of this hemoglobinopathy are usually similar to those found in the intermediate type of Cooley’s anemia; however, mild or asymptomatic cases have been reported by various investigators. 6 Singer et al.1 have described four Negro patients with m...

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Alpha thalassemia changes erythrocyte heterogeneity in sickle cell disease.

Homozygous alpha-thalassemia has the beneficial effect in sickle cell anemia of reducing the hemolytic severity while changing several other hematological parameters. We examined in detail the cellular basis of some of these hematologic alterations. We find that the broad distribution in erythrocyte density and the large proportion of dense cells associated with sickle cell anemia are both redu...

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Sickle cell-thalassemia disease in Jamaica.

SICKLE CELL-thalassemia disease was first reported by Silvestroni and Bianco in Italians in Europe.13 Cases have also been described in Italians and Greeks in the United States,48 in Negroes in Africa9 and the United States1013 and in Eti-Turks.’4 A recent paper describes 44 cases of the disease in Greece.3#{176} Sickle cell-thalassemia disease results from the inheritance of two genes, the sic...

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The First Observation of Homozygous Hemoglobin S-Alpha Thalassemia Disease and Two Types of Sickle Cell Thalassemia Disease: (a) Sickle Cell-Alpha Thalassemia Disease, (b) Sickle Cell-Beta Thalassemia Disease

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The First Observation of Homozygous Hemoglobin S-alpha Thalassemia Disease and Two Types of Sickle Cell Thalassemia Disease: (a) Sickle Cell-alpha Thalassemia Disease, (b) Sickle Cell-beta Thalassemia Disease.

The First Observation of Homozygous Hemoglobin S.Alpha Thalassemia Disease and Two Types of Sickle Cell Thalassemia Disease : (a) Sickle Cell-Alpha Thalassemia Disease, (b) Sickle Cell-Beta Thalassemia Disease

The First Observation of Homozygous Hemoglobin S . Alpha Thalassemia Disease and Two Types of Sickle Cell

Alpha thalassemia changes erythrocyte heterogeneity in sickle cell disease.

Sickle cell-thalassemia disease in Jamaica.

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