The Fight Against Sleeping Sickness 1

Agrochemicals against Malaria, Sleeping Sickness, Leishmaniasis and Chagas Disease

In tropical regions, protozoan parasites can cause severe diseases with malaria, leishmaniasis, sleeping sickness, and Chagas disease standing in the forefront. Many of the drugs currently being used to treat these diseases have been developed more than 50 years ago and can cause severe adverse effects. Above all, resistance to existing drugs is widespread and has become a serious problem threa...

Sleeping Sickness Wakes Again

Sleeping sickness of horses was, as reeentiy as the IQSO's, the most devastating livestock disease in the United States. Horses died by the hundreds of thousands in the Midwestern United States, in California, and along the Atlantic seaboard at a period which coincided with the beginning of the sharp decline in the use of horses on the farm. Losses were so severe in some areas that the inevitab...

The Sleeping Sickness of Uganda

34 cases by the same method and found the Trypanosoma in 20 cases, or 70 per cent. An examination of 12 cases of other diseases including three of Trypanosoma fever in the same way gave negative results. The matter was then taken up by" Lieutenant-Colonel David Bruce, F.n.c.s., R A M C and Dr. David N. Nabarro, who had been deputed by the Royal Society to investigate sleeping sickness, and arri...

Sleeping sickness – human African trypanosomiasis

Sleeping sickness and the central nervous system.

Chronic African trypanosomiasis is associated with progressive behavioural deficits, for which there is a complex underlying central nervous system (CNS) pathology. This has been extensively studied in man and a range of experimental animals. An initial meningitis, which can occur quite early in the infection, is followed by a breakdown of the choroid plexus, movement of the parasite into certa...