The experience of follicular occlusion syndrome treatment with tumor necrosis factor inhibitors

Follicular occlusion syndrome consists of several conditions that share similar pathophysiology involving infundibular follicular and secondary inflammatory cascade. This includes hidradenitis suppurativa, dissecting cellulitis the scalp, acne conglobata pilonidal sinus. They can develop independently or as a component in different combinations.
 We are first to present clinical case tetrad intermediate therapy outcome with tumor necrosis factor inhibitors. also provide full updated review literature on etiology pathogenesis, diagnosis treatment syndromic conditions.
 Currently, there is no reliable algorithm for patients syndrome, which underlines importance further studies. The presented confirms need timely administration genetically-engineered biological drugs diseases group (before sinus tract formation).