The Endocannabinoid System: Potential for Reducing Cardiometabolic Risk
نویسندگان
چکیده
منابع مشابه
The endocannabinoid system: a new perspective for cardiometabolic risk control.
Mailing address: emilio Antonio Francischetti • Rua Paulo César de Andrade, 106/602 22221-090 Rio de Janeiro, RJ Brazil E-mail: [email protected] Received on 04/18/06 • Accepted on 07/14/06 The prevalence of many cardiovascular risk factors has been significantly reduced in the last forty years1. Therapeutic advance gained from lipid-lowering agents, anti-hypertensive drugs, and anti-diabetic ora...
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The endocannabinoid system (EC) plays a significant role in appetite drive and associated behaviours. Therefore attenuation of the activity of the EC system would have therapeutic benefit in treating disorders that might have a component of excess appetite drive or over-activity of the endocannabinoid system, such as obesity, ethanol and other drug abuse, and a variety of central nervous system...
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The endocannabinoid system (ECS) is an endogenous physiological system composed of two cannabinoid receptors and several endogenous ligands. The ECS is intimately involved in appetite regulation and energy homeostasis, which makes it an intriguing target for pharmacological treatment of obesity, diabetes, and the metabolic syndrome. Rimonabant is the first cannabinoid receptor (CB-1) antagonist...
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A number of studies and analyses have illustrated the increased rate of cardiovascular disease conferred by multiple risk factors. 1,2 Up to now, however, the primary focus for addressing cardiovascular risk has been the treatment of each risk factor separately (e.g., LDL cholesterol, hypertension, and diabetes). Major gaps in our overall understanding of the ways in which these individual risk...
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ژورنال
عنوان ژورنال: Obesity
سال: 2009
ISSN: 1930-7381
DOI: 10.1038/oby.2009.107