The Endocannabinoid System and Liver Diseases
نویسندگان
چکیده
منابع مشابه
The role of the endocannabinoid system in liver diseases.
Endogenous cannabinoids (ECs) are ubiquitous lipid signaling molecules provided by a number of central and peripheral effects, which are mediated mainly by the specific receptors CB1 and CB2. In the last decade a considerable number of studies has shown that ECs and their receptors play an important role in the pathophysiology of liver diseases. The EC system is strongly up-regulated during chr...
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Introduction Chronic liver disease is responsible for about 800,000 deaths a year due to cirrhosis and its complications. The most common causes of liver disease worldwide are viral hepatitis, chronic alcohol consumption, and non-alcoholic fatty liver disease (NAFLD) associated with the metabolic syndrome. All these conditions generate liver injury and inflammation, thereby activating liver fib...
متن کاملThe endocannabinoid system in chronic liver disease.
Despite the public concern about the controversial use and abuse of marijuana, the scientific community has focused on the therapeutic potentials of cannabinoid compounds and had highlighted the importance of endocannabinoids and their receptors in physiology and disease. Endocannabinoids have been shown to be important mediators in neuroendocrine and psychiatric processes such as food intake, ...
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conclusions the important role played by endocannabinoid system promises interesting developments, in particular to evaluate the effectiveness of new drugs in both psychiatry and neurology. materials and methods the article is a critical analysis of the most recent data currently present in scientific literature on the subject; a qualitative synthesis of only the most significant articles has b...
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Over the last years, considerable progress has been made in understanding the role of the endocannabinoid system in the modulation of several progressive neurodegenerative diseases. The endocannabinoid system, comprised of cannabinoid receptors (type-1 and type-2), their endogenous ligands [referred to as endocannabinoids, of which anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are most stu...
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ژورنال
عنوان ژورنال: Journal of Neuroendocrinology
سال: 2008
ISSN: 0953-8194,1365-2826
DOI: 10.1111/j.1365-2826.2008.01679.x