The emerging role of copper-64 radiopharmaceuticals as cancer theranostics
نویسندگان
چکیده
منابع مشابه
The current status and future of theranostic Copper-64 radiopharmaceuticals
Copper-64 was produced in large scales and high specific activities in late 1990s’ using compact cyclotrons based by 64Ni(p,n)64Cu reaction and many radiopharmaceuticals developed since then by various groups based on interesting physicochemical and nuclear properties of the radionuclide. The unique emission of beta particles as well as positron particles offers a spectacu...
متن کاملThe current status and future of theranostic Copper-64 radiopharmaceuticals
Copper-64 was produced in large scales and high specific activities in late 1990s’ using compact cyclotrons based by 64Ni(p,n)64Cu reaction and many radiopharmaceuticals developed since then by various groups based on interesting physicochemical and nuclear properties of the radionuclide. The unique emission of beta particles as well as positron particles offers a spectacular real therapeutic/d...
متن کاملthe current status and future of theranostic copper-64 radiopharmaceuticals
copper-64 was produced in large scales and high specific activities in late 1990s’ using compact cyclotrons based by 64ni(p,n)64cu reaction and many radiopharmaceuticals developed since then by various groups based on interesting physicochemical and nuclear properties of the radionuclide. the unique emission of beta particles as well as positron particles offers a spectacular real therapeutic/d...
متن کاملMolecular imaging of cancer with copper-64 radiopharmaceuticals and positron emission tomography (PET).
Molecular imaging has evolved over the past several years into an important tool for diagnosing, understanding, and monitoring disease. Molecular imaging has distinguished itself as an interdisciplinary field, with contributions from chemistry, biology, physics, and medicine. The cross-disciplinary impetus has led to significant achievements, such as the development of more sensitive imaging in...
متن کاملCopper-64 radiopharmaceuticals for PET imaging of cancer: advances in preclinical and clinical research.
Copper-64 (T(1/2) = 12.7 hours; beta(+), 0.653 MeV [17.8 %]; beta(-), 0.579 MeV [38.4 %]) has decay characteristics that allow for positron emission tomography (PET) imaging and targeted radiotherapy of cancer. The well-established coordination chemistry of copper allows for its reaction with a wide variety of chelator systems that can potentially be linked to peptides and other biologically re...
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ژورنال
عنوان ژورنال: Drug Discovery Today
سال: 2018
ISSN: 1359-6446
DOI: 10.1016/j.drudis.2018.04.002