The efficacy of rituximab in patients with mucous membrane pemphigoid
نویسندگان
چکیده
منابع مشابه
Rituximab for patients with refractory mucous membrane pemphigoid.
BACKGROUND Mucous membrane pemphigoid (MMP) still represents a potentially life- and sight-threatening disease. In a subset of patients with severe MMP, conventional immunosuppressants are ineffective or contraindicated. OBSERVATIONS Twenty-five patients with severe refractory MMP, including 5 with mucous membrane-dominant epidermolysis bullosa acquisita, received 1 or 2 cycles of rituximab (...
متن کاملMucous membrane pemphigoid
Introduction Identifying risk factors for leprosy reactions can preempt clinicians to initiate prompt treatment to prevent associated morbidities. Thus, a retrospective study was done to elucidate the risk factors among 44 newly diagnosed leprosy patients in Sarawak General Hospital from 1993 to 2007. Materials and methods Case folders were searched for demographic data, clinical characteristic...
متن کاملSuccessful treatment of mucous membrane pemphigoid with the anti-CD-20 antibody rituximab.
101 Letters to the Editor Sir, Mucous membrane pemphigoid (MMP) is an often difficult to treat autoimmune bullous disease characterized by circulating auto-antibodies targeting the dermo-epidermal junctional zone (1–3). Due to limited disease control and/or severe adverse reactions to glucocorticoids and conventional immunosuppressants, alternative treatment options are frequently needed. We de...
متن کاملMucous membrane pemphigoid with severe esophageal stricture.
Mucous membrane pemphigoid (MMP) is a rare nosological entity. MMP consists of a clinical phenotype in which several autoimmune subepidermal bullous diseases are classified. It occurs predominantly in the mucous membranes and usually results in scarring. Esophageal involvement in MMP is rare and is generally seen in patients in whom lesions are widespread. The most common alterations are multip...
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34-year-old African American female with history of pemphigoid presented with hemoptysis. Patient was found to have mucous membrane pemphigoid involving the oropharynx and extending to trachea, till just above main stem carina. Four other cases described mucosal pemphigoid involving the trachea. We hereby present a brief review of current consensus on management of mucous membrane pemphigoid wi...
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ژورنال
عنوان ژورنال: Journal of Dermatological Treatment
سال: 2020
ISSN: 0954-6634,1471-1753
DOI: 10.1080/09546634.2020.1801974