The effects of some avermectins on bovine carbonic anhydrase enzyme
نویسندگان
چکیده
منابع مشابه
Effects of surface charge on denaturation of bovine carbonic anhydrase.
This work compares the denaturation of two proteins-bovine carbonic anhydrase II (BCA) and its derivative with all lysine groups acetylated (BCA-Ac(18))-by urea, guanidinium chloride (GuHCl), heat, and sodium dodecyl sulfate (SDS). It demonstrates that increasing the net negative charge of the protein by acetylation of lysines reduces its stability to urea, GuHCl, and heat, but increases its ki...
متن کاملEffects of pH and inhibitors on some properties related to metal binding in bovine carbonic anhydrase.
Carbonic anhydrase contains one firmly bound zinc ion per enzyme molecule (1). The metal ion, which can be dissociated in the presence of a chelating agent, is essential for catalytic activity, and it has been suggested that it is a part of the active site (2). Some other divalent metal ions also activate the metal-free enzyme. For example, Co2+ gives 45oj, of the activity of the native enzyme ...
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ژورنال
عنوان ژورنال: Journal of Enzyme Inhibition and Medicinal Chemistry
سال: 2015
ISSN: 1475-6366,1475-6374
DOI: 10.3109/14756366.2015.1064406