The Effect of Interferon Inducers on Colony Stimulating Factor Production in L Cell Cultures
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THE EFFECT OF THEOPHYLLINE ON THE PRODUCTION OF COLONY STIMULATING FACTOR (CSF)BY THE LUNG
The effect of theophylline on colony stimulating factor production by the lung tissue was investigated. Addition of various concentrations of theophylline to the lung conditioned medium enhanced CSF production at 10 µg/ml and at higher concentrations showed an inhibitory effect. Determination of the phosphate content of the medium showed a decrease at 1-3 hours of incubation. Addition of A...
متن کاملTHE ROLE OF ALVEOLAR MACROPHAGES IN THE PRODUCTION OF COLONY –STIMULATING FACTOR BY THE LUNG
The role of alveolar macrophages in the production of granulocyte/ macrophage colony-stimulating factor(s) by the rat lung was investigated. Lavaged lungs, when incubated at proper weight per volume of culture medium, produced the same amount of colony-stimulating factor as unlavaged ones. Both lavaged and unlavaged lungs produced similar types of colony-stimulating factor (s). Prolonged i...
متن کاملSTUDIES ON THE TISSUE SPECIFICITY OF COLONY STIMULATING FACTOR
In this study granulocyte-macrophage colony stimulating factor (CSF) was prepared from rabbit and guinea pig lung tissues. The biological activity of these CSFs was measured on semisolid agar culture and compared with those of mouse and rat. Weight of animals, incubation time and cross-reactivity of CSFs with different bone marrow sources were also investigated. The results showed that both...
متن کاملEffect of granulocyte-macrophage colony-stimulating growth factor on interferon and tumor necrosis factor production in whole blood cell cultures of patients with acute myelogenous leukemia.
The effect of recombinat human granulocyte-macrophage colony-stimulating growth factor (rHuGM-CSF) treatment on in vitro interferon (IFN) and tumor necrosis factor (TNF) production in peripheral blood cells of 46 patients with acute myelogenous leukemia (AML) was examined. GM-CSF significantly enhanced virus-induced IFN-alpha production in blood cells (containing 68% of blasts) of 28 patients w...
متن کاملthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1975
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-27-1-107