The effect of calorie restricted diet on anthropometric and biochemical parameters in Sprague Dawley rats

Purpose Calorie restricted diets are known to improve health and promote healthy aging. This happens because of controlled inflammation metabolism in the body. study aims evaluate differences anthropometric biochemical parameters Sprague Dawley (SD) rats consumption a calorie diet. Design/methodology/approach The divided SD ( n = 15) into 3 groups consuming high intake (HCI), medium low (LCI). Anthropometric were determined through measurement abdominal circumference (AC), thoracic (TC), body length weight (BW). Biochemical analyzed this fasting blood glucose level full lipid profile. Nutritional status was obtained based on food consumption, energy (EI) efficiency rate. Measurements taken for period four weeks. Findings Analysis indicates significant difference mean BW between HCI (230.44 ± 1.47 g) LCI (188.54 1.50 g). There is TC ratio p < 0.001; F 13.599) group (1.01 0.00714) compared (1.04 0.00858). Post hoc nutrition EI (9.71 0.006 kJ) (3.21 0.001 kJ). effect 0.0001; 3042872.02) all three groups. HDL levels significantly higher 1536.89) (68.60 0.55 mg/dL) (49.40 mg/dL). Pearson’s correlation results show strong positive with 0.01; r 0.988), AC 0.970) mass index 0.972). Originality/value Low diet has been proven affect development shown improvements rats. may result aging which could prevent later-life diseases.