The Effect of Antibiotics on Mesophilic Anaerobic Digestion Process of Cattle Manure

This study explored the effect of eight antimicrobials on efficiency biogas production in anaerobic digestion (AD) process cattle manure. The microbiome involved AD, presence and number genes mcrA, MSC MST specific for Archaea, antibiotic resistance (ARGs) concentration digestate (D) were examined. Supplementation antibiotics to substrate significantly lowered production. Amoxicillin caused a 75% decrease CH4 comparison with control samples. Enrofloxacin, tetracycline, oxytetracycline, chlortetracycline reduced amount produced by 36, 39, 45 53%, respectively. High-throughput sequencing 16S rRNA results revealed that bacteria dominated Archaea microorganisms all Moreover, led abundance MSC, MST, induced an increase tetracyclines genes. Antibiotics decreased AD quantity obtained, while stimulating ARGs D. work reveals how affect manure changes microbial biodiversity, functional due drugs exposure. It also, provides useful, practical information about process.