منابع مشابه
Anti-tumor Activity of Tylophora Asthmatica
T. asthmatica, which belongs to the family Asclepiadaceae is a small twining a plant with long fleshy roots. The plant shows broad activity against EA and DLA cells. The intraperitoneal injection of PE extract obtained from the powdered entire plant material to the tumor cell transplanted animals arrests the tumor growth and prevents the formation of the tumor. A significant increase in the lif...
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Alternative splicing has emerged as an important target for molecular therapies. Splice-switching oligonucleotides (SSOs) modulate alternative splicing by hybridizing to pre-mRNA sequences involved in splicing and blocking access to the transcript by splicing factors. Recently, the efficacy of SSOs has been established in various animal disease models; however, the application of SSOs against c...
متن کاملIron Induces Anti-tumor Activity in Tumor-Associated Macrophages
Tumor-associated macrophages (TAMs) frequently help to sustain tumor growth and mediate immune suppression in the tumor microenvironment (TME). Here, we identified a subset of iron-loaded, pro-inflammatory TAMs localized in hemorrhagic areas of the TME. The occurrence of iron-loaded TAMs (iTAMs) correlated with reduced tumor size in patients with non-small cell lung cancer. Ex vivo experiments ...
متن کاملAnti-nociceptive and anti-inflamatory activity of olive fruit extract
In Iranian traditional medicine, olive has been reported to have analgesic and anti-inflamatory effects. In the present study the anti-nociceptive and anti-inflamatory effects of olive fruit has been studied. In this study the methanolic and aqueous extract of the fruit with HER (Herbal to Extract Ratio) of 4.96% and 4.84% has been used and analgesic effect of this extract has been compared wit...
متن کاملAnti-Nociceptive and Anti-Inflammatory Activity of Araucaria bidwillii Hook
The effect of alcoholic extracts of leaf from Araucaria bidwillii Hook. [ABH] (Family: Araucariaceae) was evaluated in experimental models of pain and inflammation. Oral administration of 100, 200 and 300 mg/kg of leaf extracts of ABH were used for the above study. The leaf extract at 300 and 200 mg/kg showed significant reduction in acetic acid induced writhings in mice with a maximum effect o...
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ژورنال
عنوان ژورنال: Okayama Igakkai Zasshi (Journal of Okayama Medical Association)
سال: 1959
ISSN: 0030-1558,1882-4528
DOI: 10.4044/joma1947.71.6-2_3327